Atogepant Is Not Associated With Clinically Meaningful Alanine Aminotransferase Elevations in Healthy Adults

Atogepant is a potent, selective, oral calcitonin gene–related peptide (CGRP) receptor antagonist in development for migraine prevention. The chemical structure of atogepant is distinct from previous CGRP receptor antagonists, which were associated with elevated serum alanine aminotransferase (ALT)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Transl Sci
Egile Nagusiak: Min, K. Chris, Kraft, Walter K., Bondiskey, Phung, Colón‐González, Francheska, Liu, Wen, Xu, Jialin, Panebianco, Deborah, Mixson, Lori, Dockendorf, Marissa F., Matthews, Catherine Z., Boinpally, Ramesh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993278/
https://ncbi.nlm.nih.gov/pubmed/33142014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12917
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