Atogepant Is Not Associated With Clinically Meaningful Alanine Aminotransferase Elevations in Healthy Adults

Atogepant is a potent, selective, oral calcitonin gene–related peptide (CGRP) receptor antagonist in development for migraine prevention. The chemical structure of atogepant is distinct from previous CGRP receptor antagonists, which were associated with elevated serum alanine aminotransferase (ALT)...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Min, K. Chris, Kraft, Walter K., Bondiskey, Phung, Colón‐González, Francheska, Liu, Wen, Xu, Jialin, Panebianco, Deborah, Mixson, Lori, Dockendorf, Marissa F., Matthews, Catherine Z., Boinpally, Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993278/
https://ncbi.nlm.nih.gov/pubmed/33142014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12917
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