MUKnine OPTIMUM protocol: a screening study to identify high-risk patients with multiple myeloma suitable for novel treatment approaches combined with a phase II study evaluating optimised combination of biological therapy in newly diagnosed high-risk multiple myeloma and plasma cell leukaemia

INTRODUCTION: Multiple myeloma (MM) is a plasma cell tumour with over 5800 new cases each year in the UK. The introduction of biological therapies has improved outcomes for the majority of patients with MM, but in approximately 20% of patients the tumour is characterised by genetic changes which con...

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Bibliographic Details
Published in:BMJ Open
Main Authors: Brown, Sarah, Sherratt, Debbie, Hinsley, Samantha, Flanagan, Louise, Roberts, Sadie, Walker, Katrina, Hall, Andrew, Pratt, Guy, Messiou, Christina, Jenner, Matthew, Kaiser, Martin
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2021
Subjects:
Haematology (Incl Blood Transfusion)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993167/
https://ncbi.nlm.nih.gov/pubmed/33762245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-046225
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