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MUKnine OPTIMUM protocol: a screening study to identify high-risk patients with multiple myeloma suitable for novel treatment approaches combined with a phase II study evaluating optimised combination of biological therapy in newly diagnosed high-risk multiple myeloma and plasma cell leukaemia

INTRODUCTION: Multiple myeloma (MM) is a plasma cell tumour with over 5800 new cases each year in the UK. The introduction of biological therapies has improved outcomes for the majority of patients with MM, but in approximately 20% of patients the tumour is characterised by genetic changes which con...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Brown, Sarah, Sherratt, Debbie, Hinsley, Samantha, Flanagan, Louise, Roberts, Sadie, Walker, Katrina, Hall, Andrew, Pratt, Guy, Messiou, Christina, Jenner, Matthew, Kaiser, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993167/
https://ncbi.nlm.nih.gov/pubmed/33762245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-046225
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