Tumor regression and immunity in combination therapy with anti-CEA chimeric antigen receptor T cells and anti-CEA-IL2 immunocytokine

Targeted immunotherapy of solid cancers with chimeric antigen receptor (CAR) T cells and immunocytokines are attractive options in that they both rely on the specificity of tumor-targeted antibodies. Since carcinoembryonic antigen (CEA) expression in both colon and breast cancers is correlated with...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Cha, Seung E., Kujawski, Maciej, J. Yazaki, Paul, Brown, Christine, Shively, John E.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2021
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993151/
https://ncbi.nlm.nih.gov/pubmed/33796409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1899469
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