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Using mitochondrial activity to select for potent human hematopoietic stem cells

Hematopoietic cell transplantation is a critical curative approach for many blood disorders. However, obtaining grafts with sufficient numbers of hematopoietic stem cells (HSCs) that maintain long-term engraftment remains challenging; this is due partly to metabolic modulations that restrict the pot...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Qiu, Jiajing, Gjini, Jana, Arif, Tasleem, Moore, Kateri, Lin, Miao, Ghaffari, Saghi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993096/
https://ncbi.nlm.nih.gov/pubmed/33710339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003658
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