GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase

BACKGROUND: Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate. Tumor cells that acquire the ability to metabolize fructose have a fitness advantage over their neighboring cells, but the proteins that mediate f...

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Detalhes bibliográficos
Publicado no:Cancer Metab
Main Authors: Liang, Roger J., Taylor, Samuel, Nahiyaan, Navid, Song, Junho, Murphy, Charles J., Dantas, Ezequiel, Cheng, Shuyuan, Hsu, Ting-Wei, Ramsamooj, Shakti, Grover, Rahul, Hwang, Seo-Kyoung, Ngo, Bryan, Cantley, Lewis C., Rhee, Kyu Y., Goncalves, Marcus D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992954/
https://ncbi.nlm.nih.gov/pubmed/33762003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00246-9
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