GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase

BACKGROUND: Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate. Tumor cells that acquire the ability to metabolize fructose have a fitness advantage over their neighboring cells, but the proteins that mediate f...

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Библиографические подробности
Опубликовано в: :Cancer Metab
Главные авторы: Liang, Roger J., Taylor, Samuel, Nahiyaan, Navid, Song, Junho, Murphy, Charles J., Dantas, Ezequiel, Cheng, Shuyuan, Hsu, Ting-Wei, Ramsamooj, Shakti, Grover, Rahul, Hwang, Seo-Kyoung, Ngo, Bryan, Cantley, Lewis C., Rhee, Kyu Y., Goncalves, Marcus D.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2021
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992954/
https://ncbi.nlm.nih.gov/pubmed/33762003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00246-9
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