Epidermal growth factor receptor as a molecular determinant of glioblastoma response to dopamine receptor D2 inhibitors

BACKGROUND: There are ongoing clinical trials exploring the efficacy of dopamine receptor D2 (DRD2) inhibition against glioblastomas, the most common primary brain tumor. Here we examine potential molecular determinants of this efficacy. METHODS: The Cancer Genome Atlas glioblastoma database and oth...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: He, Yuyu, Li, Jie, Koga, Tomoyuki, Ma, Jun, Dhawan, Sanjay, Suzuki, Yuta, Furnari, Frank, Prabhu, Varun V, Allen, Joshua E, Chen, Clark C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992877/
https://ncbi.nlm.nih.gov/pubmed/32830856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa188
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