High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

BACKGROUND: Characterization of breast cancer (BC) through the determination of conventional markers such as ER, PR, HER2, and Ki67 has been useful as a predictive and therapeutic tool. Also, assessment of tumor-infiltrating lymphocytes has been proposed as an important prognostic aspect to be consi...

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Publicado en:Breast Cancer Res
Autores principales: Gatti, Gerardo, Betts, Courtney, Rocha, Darío, Nicola, Maribel, Grupe, Verónica, Ditada, Cecilia, Nuñez, Nicolas G., Roselli, Emiliano, Araya, Paula, Dutto, Jeremías, Boffelli, Lucia, Fernández, Elmer, Coussens, Lisa M., Maccioni, Mariana
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992828/
https://ncbi.nlm.nih.gov/pubmed/33766090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-021-01418-7
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