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Platycodin D May Improve Acne and Prevent Scarring by Downregulating SREBP-1 Expression Via Inhibition of IGF-1R/PI3K/Akt Pathway and Modulating Inflammation with an Increase in Collagen

BACKGROUND: Although many therapeutic agents have been developed, only a few drugs are known to target multiple pathogenic factors in the treatment of acne. OBJECTIVE: The purpose of this study was to identify a new drug candidate, platycodin D, which is a substance extracted from the root of Platyc...

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Vydáno v:Ann Dermatol
Hlavní autoři: Suh, Yoorock, Yang, Ji Hoon, Yoon, Ji Young, Choi, Yu Sung
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992470/
https://ncbi.nlm.nih.gov/pubmed/33911482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5021/ad.2018.30.5.581
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