DDRE-28. MECHANISTIC AND THERAPEUTIC LINKS BETWEEN PURINE BIOSYNTHESIS AND DNA DAMAGE IN GLIOBLASTOMA

Glioblastoma (GBM) is the most common and aggressive adult brain cancer. Radiation therapy (RT) is a critical treatment modality, and development of RT resistance is the predominant cause of recurrence and mortality in GBM patients. Using cell line models as well as patient-derived xenografts and ne...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Scott, Andrew, Zhou, Weihua, Wilder-Romans, Kari, Feng, Jiane, Wu, Zhe, Andren, Anthony, Zhang, Li, Sajjakulnukit, Peter, Kachman, Maureen, Umemura, Yoshie, Schmitt, Melanie, Qi, Nathan, Lawrence, Theodore, Lyssiotis, Costas, Wahl, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Supplement Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992234/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.050
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