FSMP-01. ID1 MEDIATES ONE-CARBON MEDIATED PURINE SYNTHESIS IN GLIOBLASTOMA

Inhibitor of DNA-binding-1 (ID1) is a transcriptional regulatory protein involved in maintenance of self-renewal and inhibition of differentiation, and acts as a key regulator of tumorigenesis in glioblastoma. Studies suggest that de novo purine synthesis is essential for the maintenance of rapid pr...

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Bibliographic Details
Published in:Neurooncol Adv
Main Authors: Ghannad-Zadeh, Kimia, Wu, Megan, Wilson, Taylor, Flick, Robert, Das, Sunit
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992210/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.066
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