Power of an Organic Electron Acceptor in Modulation of Intracellular Mitochondrial Reactive Oxygen Species: Inducing JNK- and Caspase-Dependent Apoptosis of Cancer Cells

[Image: see text] Here, we demonstrate an interesting strategy of modulating mitochondrial reactive oxygen species (ROS) using the organic electron acceptor molecule carbonyl-bridged bithiazole attached with bis-trifluoroacetophenone (BBT). This molecule was found to affect complex I activity. It ha...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Mohapatra, Saswat, Das, Gaurav, Gupta, Varsha, Mondal, Prasenjit, Nitani, Masashi, Ie, Yutaka, Chatterjee, Shreyam, Aso, Yoshio, Ghosh, Surajit
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992140/
https://ncbi.nlm.nih.gov/pubmed/33778293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c00308
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