Effect of gold nanoparticles on the structure and neuroprotective function of protein L-isoaspartyl methyltransferase (PIMT)

Fibrillation of peptides and proteins is implicated in various neurodegenerative diseases and is a global concern. Aging leads to the formation of abnormal isoaspartate (isoAsp) residues from isomerization of normal aspartates in proteins, triggering fibril formation that leads to neurodegenerative...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chatterjee, Tanaya, Das, Gaurav, Ghosh, Surajit, Chakrabarti, Pinak
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275801/
https://ncbi.nlm.nih.gov/pubmed/34253804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93752-1
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