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The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

In this protocol, we detail the correct procedural steps and necessary precautions to successfully perform a left pneumonectomy and induce PAH in rats with the additional administration of monocrotaline (MCT) or SU5416 (Sugen). We also compare these two models to other PAH models commonly used in re...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Vis Exp
Asıl Yazarlar: Katz, Michael G., Fargnoli, Anthony S., Gubara, Sarah M., Bisserier, Malik, Sassi, Yassine, Bridges, Charles R., Hajjar, Roger J., Hadri, Lahouaria
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992111/
https://ncbi.nlm.nih.gov/pubmed/30907889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59050
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