Opposing Effects of TGFβ and BMP in the Pulmonary Vasculature in Congenital Diaphragmatic Hernia

Background: Pulmonary hypertension is the major cause of morbidity and mortality in congenital diaphragmatic hernia (CDH). Mutations in several genes that encode signaling molecules of the transforming growth factor β (TGFβ) and bone morphogenetic protein (BMP) pathways have previously been associat...

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Bibliographic Details
Published in:Front Med (Lausanne)
Main Authors: Mous, Daphne S., Buscop-van Kempen, Marjon J., Wijnen, Rene M. H., Tibboel, Dick, Morty, Rory E., Rottier, Robbert J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7991367/
https://ncbi.nlm.nih.gov/pubmed/33777983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2021.642577
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