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Telomere Length in Valve Tissue Is Shorter in Individuals With Aortic Stenosis and in Calcified Valve Areas

BACKGROUND: Short telomere length (TL) is associated with age-related diseases, in particular cardiovascular diseases. However, whether the onset and course of aortic stenosis (AS) is linked to TL in aortic valves remains unknown. OBJECTIVES: To assess telomere dynamics (TL and telomerase activity)...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Saraieva, Ilona, Benetos, Athanase, Labat, Carlos, Franco-Cereceda, Anders, Bäck, Magnus, Toupance, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990782/
https://ncbi.nlm.nih.gov/pubmed/33777932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.618335
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