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Changes in DNA methylation accompany changes in gene expression during chondrocyte hypertrophic differentiation in vitro.

During osteoarthritis (OA), articular chondrocytes undergo phenotypic changes that resemble developmental patterns characteristic of growth plate chondrocytes. These phenotypic alterations lead to a hypertrophy-like phenotype characterized by altered production of extracellular matrix constituents a...

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Detalles Bibliográficos
Publicado en:Ann N Y Acad Sci
Main Authors: Singh, Purva, Lessard, Samantha G., Mukherjee, Piali, Rourke, Brennan, Otero, Miguel
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990741/
https://ncbi.nlm.nih.gov/pubmed/32978775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.14494
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