Detection of Endothelial Cell-Associated Human DNA Reveals Transplanted Human Bone Marrow Stem Cell Engraftment into CNS Capillaries of ALS Mice

Repairing the altered blood-CNS-barrier in amyotrophic lateral sclerosis (ALS) is imperative to prevent entry of detrimental blood-borne substances into the CNS. Cell transplantation with the goal of replacing damaged endothelial cells (ECs) may be a new therapeutic approach for barrier restoration....

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Publicado en:Brain Res Bull
Autores principales: Garbuzova-Davis, Svitlana, Boccio, Kayla J., Ehrhart, Jared, Sanberg, Paul R., Appel, Stanley H., Borlongan, Cesario V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990719/
https://ncbi.nlm.nih.gov/pubmed/33545308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2021.01.020
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