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Intravenously Transplanted Human Bone Marrow Endothelial Progenitor Cells Engraft Within Brain Capillaries, Preserve Mitochondrial Morphology, and Display Pinocytotic Activity Towards BBB Repair in Ischemic Stroke Rats

Stroke is a life threatening disease with limited therapeutic options. Cell therapy has emerged as an experimental stroke treatment. Blood-brain barrier (BBB) impairment is a key pathological manifestation of ischemic stroke, and barrier repair is an innovative target for neurorestoration in stroke....

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Publicat a:Stem Cells
Autors principals: Garbuzova-Davis, Svitlana, Haller, Edward, Lin, Roger, Borlongan, Cesario V.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404940/
https://ncbi.nlm.nih.gov/pubmed/28142208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2578
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