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Nilotinib Improves Bioenergetic Profiling in Brain Astroglia in the 3xTg Mouse Model of Alzheimer’s Disease

Current treatments targeting amyloid beta in Alzheimer’s disease (AD) have minimal efficacy, which results in a huge unmet medical need worldwide. Accumulating data suggest that brain mitochondrial dysfunction play a critical role in AD pathogenesis. Targeting cellular mechanisms associated with mit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging Dis
Hauptverfasser: Adlimoghaddam, Aida, Odero, Gary G, Glazner, Gordon, Turner, R. Scott, Albensi, Benedict C
Format: Artigo
Sprache:Inglês
Veröffentlicht: JKL International LLC 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990369/
https://ncbi.nlm.nih.gov/pubmed/33815876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2020.0910
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