Ca(2+) signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG

Calcium signaling regulated by the cGMP-dependent protein kinase (PKG) controls key life cycle transitions in the malaria parasite. However, how calcium is mobilized from intracellular stores in the absence of canonical calcium channels in Plasmodium is unknown. Here, we identify a multipass membran...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Balestra, Aurélia C., Koussis, Konstantinos, Klages, Natacha, Howell, Steven A., Flynn, Helen R., Bantscheff, Marcus, Pasquarello, Carla, Perrin, Abigail J., Brusini, Lorenzo, Arboit, Patrizia, Sanz, Olalla, Castaño, Laura Peces-Barba, Withers-Martinez, Chrislaine, Hainard, Alexandre, Ghidelli-Disse, Sonja, Snijders, Ambrosius P., Baker, David A., Blackman, Michael J., Brochet, Mathieu
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990342/
https://ncbi.nlm.nih.gov/pubmed/33762339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe5396
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki