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Biology drives the discovery of bispecific antibodies as innovative therapeutics

A bispecific antibody (bsAb) is able to bind two different targets or two distinct epitopes on the same target. Broadly speaking, bsAbs can include any single molecule entity containing dual specificities with at least one being antigen-binding antibody domain. Besides additive effect or synergistic...

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Detalhes bibliográficos
Publicado no:Antib Ther
Main Authors: Nie, Siwei, Wang, Zhuozhi, Moscoso-Castro, Maria, D'Souza, Paul, Lei, Can, Xu, Jianqing, Gu, Jijie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990219/
https://ncbi.nlm.nih.gov/pubmed/33928225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tbaa003
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