Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin

Neuronal damage is a major consequence of bacterial meningitis, but little is known about mechanisms of bacterial interaction with neurons leading to neuronal cell death. Streptococcus pneumoniae (pneumococcus) is a leading cause of bacterial meningitis and many survivors develop neurological sequel...

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Vydáno v:PLoS Pathog
Hlavní autoři: Tabusi, Mahebali, Thorsdottir, Sigrun, Lysandrou, Maria, Narciso, Ana Rita, Minoia, Melania, Srambickal, Chinmaya Venugopal, Widengren, Jerker, Henriques-Normark, Birgitta, Iovino, Federico
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990213/
https://ncbi.nlm.nih.gov/pubmed/33760879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009432
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