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Resveratrol Reduces COMPopathy in Mice Through Activation of Autophagy

Misfolding mutations in cartilage oligomeric matrix protein (COMP) cause it to be retained within the endoplasmic reticulum (ER) of chondrocytes, stimulating a multitude of damaging cellular responses including ER stress, inflammation, and oxidative stress, which ultimately culminates in the death o...

詳細記述

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書誌詳細
出版年:JBMR Plus
主要な著者: Hecht, Jacqueline T, Coustry, Francoise, Veerisetty, Alka C, Hossain, Mohammad G, Posey, Karen L
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990140/
https://ncbi.nlm.nih.gov/pubmed/33778324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10456
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