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Integration of metabolomics and transcriptomics reveals convergent pathways driving radiation-induced salivary gland dysfunction

Radiation therapy for head and neck cancer causes damage to the surrounding salivary glands, resulting in salivary gland hypofunction and xerostomia. Current treatments do not provide lasting restoration of salivary gland function following radiation; therefore, a new mechanistic understanding of th...

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Vydáno v:Physiol Genomics
Hlavní autoři: Meeks, Lauren, De Oliveira Pessoa, Diogo, Martinez, Jessica A., Limesand, Kirsten H., Padi, Megha
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988743/
https://ncbi.nlm.nih.gov/pubmed/33522389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00127.2020
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