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Restoration of radiation therapy-induced salivary gland dysfunction in mice by post therapy IGF-1 administration

BACKGROUND: Radiotherapy for head and neck cancer results in severe and chronic salivary gland dysfunction in most individuals. This results in significant side effects including xerostomia, dysphagia, and malnutrition which are linked to significant reductions in patients' quality of life. Cur...

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Detalhes bibliográficos
Main Authors: Grundmann, Oliver, Fillinger, Jamia L, Victory, Kerton R, Burd, Randy, Limesand, Kirsten H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087323/
https://ncbi.nlm.nih.gov/pubmed/20698985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-417
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