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Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle

Microtubules tune cytoskeletal stiffness, which affects cytoskeletal mechanics and mechanotransduction of striated muscle. While recent evidence suggests that microtubules enriched in detyrosinated α-tubulin regulate these processes in healthy muscle and increase them in disease, the possible contri...

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Dettagli Bibliografici
Pubblicato in:J Gen Physiol
Autori principali: Coleman, Andrew K., Joca, Humberto C., Shi, Guoli, Lederer, W. Jonathan, Ward, Christopher W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988512/
https://ncbi.nlm.nih.gov/pubmed/33740038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012743
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