Maternal Diabetes Impairs Insulin and IGF-1 Receptor Expression and Signaling in Human Placenta

BACKGROUND: Maternal high blood glucose during pregnancy increases the risk for both maternal and fetal adverse outcomes. The mechanisms underlying the regulator effects of hyperglycemia on placental development and growth have not been fully illustrated yet. The placenta expresses high amounts of b...

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Bibliografiske detaljer
Udgivet i:Front Endocrinol (Lausanne)
Main Authors: Tumminia, Andrea, Scalisi, Nunzio M., Milluzzo, Agostino, Ettore, Giuseppe, Vigneri, Riccardo, Sciacca, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988311/
https://ncbi.nlm.nih.gov/pubmed/33776919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.621680
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