Extracellular HMGB1 Contributes to the Chronic Cardiac Allograft Vasculopathy/Fibrosis by Modulating TGF-β1 Signaling

Cardiac allograft vasculopathy (CAV) charactered with aberrant remodeling and fibrosis usually leads to the loss of graft after heart transplantation. Our previous work has reported that extracellular high-mobility group box 1 (HMGB1) participated in the CAV progression via promoting inflammatory ce...

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Vydáno v:Front Immunol
Hlavní autoři: Zou, Huijuan, Ming, Bingxia, Li, Jun, Xiao, Yifan, Lai, Lin, Gao, Ming, Xu, Yong, Tan, Zheng, Gong, Feili, Zheng, Fang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988222/
https://ncbi.nlm.nih.gov/pubmed/33777037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.641973
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