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Ghrelin Inhibits Intestinal Epithelial Cell Apoptosis Through the Unfolded Protein Response Pathway in Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that occurs in the lining of the rectum and colon. Apoptosis of the intestinal epithelial cells (IECs) is common in active UC patients. Ghrelin is reported to be downregulated in apoptosis of IECs induced by tumor necrosis factor-...

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Vydáno v:Front Pharmacol
Hlavní autoři: Zhang, Lin, Cheng, Jian, Shen, Jie, Wang, Sheng, Guo, Chuanyong, Fan, Xiaoming
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988211/
https://ncbi.nlm.nih.gov/pubmed/33776781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.661853
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