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Ghrelin Inhibits Intestinal Epithelial Cell Apoptosis Through the Unfolded Protein Response Pathway in Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that occurs in the lining of the rectum and colon. Apoptosis of the intestinal epithelial cells (IECs) is common in active UC patients. Ghrelin is reported to be downregulated in apoptosis of IECs induced by tumor necrosis factor-...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhang, Lin, Cheng, Jian, Shen, Jie, Wang, Sheng, Guo, Chuanyong, Fan, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988211/
https://ncbi.nlm.nih.gov/pubmed/33776781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.661853
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