Characterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS

Liquid droplets of aggregation-prone proteins, which become hydrogels or form amyloid fibrils, are a potential target for drug discovery. In this study, we proposed an experiment-guided protocol for characterizing the design grammar of peptides that can regulate droplet formation and aggregation. Th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kamagata, Kiyoto, Chiba, Rika, Kawahata, Ichiro, Iwaki, Nanako, Kanbayashi, Saori, Maeda, Kana, Takahashi, Hiroto, Hirano, Atsushi, Fukunaga, Koji, Ikeda, Keisuke, Kameda, Tomoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988016/
https://ncbi.nlm.nih.gov/pubmed/33758287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86098-1
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