SIRT1 attenuates renal fibrosis by repressing HIF-2α

Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase belonging to class III histone deacetylases. Previous studies have shown that SIRT1 is involved in kidney physiology regulation and protects the kidney from various pathological factors. However, the underlying m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Discov
Prif Awduron: Li, Peipei, Liu, Yue, Qin, Xiaogang, Chen, Kairen, Wang, Ruiting, Yuan, Li, Chen, Xiaolan, Hao, Chuanming, Huang, Xinzhong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987992/
https://ncbi.nlm.nih.gov/pubmed/33758176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00443-x
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