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Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis

Synthetic glucocorticoids (GCs), one of the most effective treatments for chronic inflammatory and autoimmune conditions in children, have adverse effects on the growing skeleton. GCs inhibit angiogenesis in growing bone, but the underlying mechanisms remain unclear. Here, we show that GC treatment...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Liu, Xiaonan, Chai, Yu, Liu, Guanqiao, Su, Weiping, Guo, Qiaoyue, Lv, Xiao, Gao, Peisong, Yu, Bin, Ferbeyre, Gerardo, Cao, Xu, Wan, Mei
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987975/
https://ncbi.nlm.nih.gov/pubmed/33758201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22131-1
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