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Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis

Synthetic glucocorticoids (GCs), one of the most effective treatments for chronic inflammatory and autoimmune conditions in children, have adverse effects on the growing skeleton. GCs inhibit angiogenesis in growing bone, but the underlying mechanisms remain unclear. Here, we show that GC treatment...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Xiaonan, Chai, Yu, Liu, Guanqiao, Su, Weiping, Guo, Qiaoyue, Lv, Xiao, Gao, Peisong, Yu, Bin, Ferbeyre, Gerardo, Cao, Xu, Wan, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987975/
https://ncbi.nlm.nih.gov/pubmed/33758201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22131-1
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