PAR2 Activation on Human Kidney Tubular Epithelial Cells Induces Tissue Factor Synthesis, That Enhances Blood Clotting

Coagulation abnormalities and increased risk of atherothrombosis are common in patients with chronic kidney diseases (CKD). Mechanisms that alter renal hemostasis and lead to thrombotic events are not fully understood. Here we show that activation of protease activated receptor-2 (PAR2) on human kid...

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Foilsithe in:Front Physiol
Main Authors: Iyer, Abishek, Humphries, Tyrone L. R., Owens, Evan P., Zhao, Kong-Nan, Masci, Paul P., Johnson, David W., Nikolic-Paterson, David, Gobe, Glenda C., Fairlie, David P., Vesey, David A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Physiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987918/
https://ncbi.nlm.nih.gov/pubmed/33776786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.615428
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