Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines

Expression of the protease sensing receptor, protease activated receptor-2 (PAR2), is elevated in a variety of cancers and has been promoted as a potential therapeutic target. With the development of potent antagonists for this receptor, we hypothesised that they could be used to treat renal cell ca...

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Publicado en:PLoS One
Main Authors: Morais, Christudas, Rajandram, Retnagowri, Blakeney, Jade S., Iyer, Abishek, Suen, Jacky Y., Johnson, David W., Gobe, Glenda C., Fairlie, David P., Vesey, David A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993771/
https://ncbi.nlm.nih.gov/pubmed/33765016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248983
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