Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma

Dysregulated amino acids metabolism reciprocally interplays with evolutionary phenotypic characteristics of cancer cells to enhance metastasis. The high metastasis potential of oral squamous cell carcinoma (OSCC) can manifest with perineural invasion (PNI). We here aimed to determine the role of ami...

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Udgivet i:Front Oncol
Main Authors: Fu, Yong, Ding, Liang, Yang, Xihu, Ding, Zhuang, Huang, Xiaofeng, Zhang, Lei, Chen, Sheng, Hu, Qingang, Ni, Yanhong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987891/
https://ncbi.nlm.nih.gov/pubmed/33777794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.637226
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