Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway

BACKGROUND: Local resident normal fibroblasts (NFs) are the major source of cancer-associated fibroblasts (CAFs), which are distinguishable from NFs by their tumor-supportive properties. However, the mechanism and the effects underlying the transition of NFs to CAFs in oral squamous cell carcinoma (...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wang, Yujia, Jing, Yue, Ding, Liang, Zhang, Xiaoxin, Song, Yuxian, Chen, Sheng, Zhao, Xingxing, Huang, Xiaofeng, Pu, Yumei, Wang, Zhiyong, Ni, Yanhong, Hu, Qingang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591968/
https://ncbi.nlm.nih.gov/pubmed/31234944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1277-x
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