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KIF21A pathogenic variants cause Congenital Fibrosis of Extraocular Muscles type 3

BACKGROUND: Congenital fibrosis of the extraocular muscles(CFEOM) is characterized by ptosis and non-progressive restrictive ophthalmoplegia. CFEOM1 is a stereotypical phenotype with isolated bilateral ptosis, bilateral ophthalmoplegia, absent upgaze, and globe infraduction. CFEOM3 is a more variabl...

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Detalhes bibliográficos
Publicado no:Ophthalmic Genet
Main Authors: Al-Haddad, Christiane, Boustany, Rose-Mary, Rachid, Elza, Ismail, Karine, Barry, Brenda, Chan, Wai-Man, Engle, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987873/
https://ncbi.nlm.nih.gov/pubmed/33251926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13816810.2020.1852576
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