Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) risk stratification in individuals with dysmetabolism is a major unmet need. Genetic predisposition contributes to non-alcoholic fatty liver disease (NAFLD). We aimed to exploit robust polygenic risk scores (PRS) that can be evaluated in the clin...

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發表在:J Hepatol
Main Authors: Bianco, Cristiana, Jamialahmadi, Oveis, Pelusi, Serena, Baselli, Guido, Dongiovanni, Paola, Zanoni, Irene, Santoro, Luigi, Maier, Silvia, Liguori, Antonio, Meroni, Marica, Borroni, Vittorio, D’Ambrosio, Roberta, Spagnuolo, Rocco, Alisi, Anna, Federico, Alessandro, Bugianesi, Elisabetta, Petta, Salvatore, Miele, Luca, Vespasiani-Gentilucci, Umberto, Anstee, Quentin M., Stickel, Felix, Hampe, Jochen, Fischer, Janett, Berg, Thomas, Fracanzani, Anna Ludovica, Soardo, Giorgio, Reeves, Helen, Prati, Daniele, Romeo, Stefano, Valenti, Luca
格式: Artigo
語言:Inglês
出版: Elsevier 2021
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987554/
https://ncbi.nlm.nih.gov/pubmed/33248170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2020.11.024
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