Protein phosphatase 1 regulatory subunit 3B gene variation protects against hepatic fat accumulation and fibrosis in individuals at high risk of nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver damage and has a strong genetic component. The rs4841132 G>A variant, modulating the expression of protein phosphatase 1 regulatory subunit 3B (PPP1R3B), which is involved in glycogen synthesis, has been reported to reduce the ris...

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Detaylı Bibliyografya
Yayımlandı:Hepatol Commun
Asıl Yazarlar: Dongiovanni, Paola, Meroni, Marica, Mancina, Rosellina M., Baselli, Guido, Rametta, Raffaela, Pelusi, Serena, Männistö, Ville, Fracanzani, Anna L., Badiali, Sara, Miele, Luca, Grimaudo, Stefania, Petta, Salvatore, Bugianesi, Elisabetta, Soardo, Giorgio, Fargion, Silvia, Pihlajamäki, Jussi, Romeo, Stefano, Valenti, Luca
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983109/
https://ncbi.nlm.nih.gov/pubmed/29881818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1192
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