Magnesium Treatment on Methylation Changes of Transmembrane Serine Protease 2 (TMPRSS2)

BACKGROUND: The viral entry of SARS-CoV-2 requires host-expressed TMPRSS2 to facilitate the viral spike (S) protein priming. OBJECTIVES: To test the hypothesis that Mg treatment leads to DNA methylation changes in TMPRSS2 . METHODS: This study is nested within the Personalized Prevention of Colorect...

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Vydáno v:medRxiv
Hlavní autoři: Fan, Lei, Zhu, Xiangzhu, Zheng, Yinan, Zhang, Wei, Seidner, Douglas L, Ness, Reid, Murff, Harvey J, Yu, Chang, Huang, Xiang, Shrubsole, Martha J, Hou, Lifang, Dai, Qi
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987044/
https://ncbi.nlm.nih.gov/pubmed/33758885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.11.21253287
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