High-resolution epigenome analysis in nasal samples derived from children with respiratory viral infections reveals striking changes upon SARS-CoV-2 infection

BACKGROUND: DNA methylation patterns of the human genome can be modified by environmental stimuli and provide dense information on gene regulatory circuitries. We studied genome-wide DNA methylation in nasal samples from infants (<6 months) applying whole-genome bisulfite sequencing (WGBS) to cha...

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Pubblicato in:medRxiv
Autori principali: Winkley, Konner, Koseva, Boryana, Banerjee, Dithi, Cheung, Warren, Selvarangan, Rangaraj, Pastinen, Tomi, Grundberg, Elin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987039/
https://ncbi.nlm.nih.gov/pubmed/33758880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.09.21253155
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