Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants

High-throughput genomics of SARS-CoV-2 is essential to characterize virus evolution and to identify adaptations that affect pathogenicity or transmission. While single-nucleotide variations (SNVs) are commonly considered as driving virus adaption, RNA recombination events that delete or insert nucle...

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Publicat a:bioRxiv
Autors principals: Jaworski, Elizabeth, Langsjoen, Rose M., Mitchell, Brooke, Judy, Barbara, Newman, Patrick, Plante, Jessica A., Plante, Kenneth S., Miller, Aaron L., Zhou, Yiyang, Swetnam, Daniele, Sotcheff, Stephanea, Morris, Victoria, Saada, Nehad, Machado, Rafael, McConnell, Allan, Widen, Steve, Thompson, Jill, Dong, Jianli, Ren, Ping, Pyles, Rick B., Ksiazek, Thomas, Menachery, Vineet D., Weaver, Scott C., Routh, Andrew
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987005/
https://ncbi.nlm.nih.gov/pubmed/33758846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.10.434828
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