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Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus

Defective-Interfering RNAs (DI-RNAs) have long been known to play an important role in virus replication and transmission. DI-RNAs emerge during virus passaging in both cell-culture and their hosts as a result of non-homologous RNA recombination. However, the principles of DI-RNA emergence and their...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Jaworski, Elizabeth, Routh, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435362/
https://ncbi.nlm.nih.gov/pubmed/28475646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006365
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