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Investigating differences between tamoxifen resistant and sensitive breast cancer cells with flow cytometry

The active metabolite of tamoxifen, 4‐hydroxytamoxifen, functions as an anti‐estrogen in breast cancer cells and thus inhibits proliferation. While tamoxifen continues to be successfully used to treat estrogen‐dependent breast cancer, most patients receiving treatment will develop chemoresistance ov...

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Pubblicato in:Cytometry A
Autori principali: Bitton, Aric, Zheng, Yan, Houston, Jessica P., Houston, Kevin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986838/
https://ncbi.nlm.nih.gov/pubmed/33508166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.24306
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