Polymeric Pathogen-Like Particles-Based Combination Adjuvants Elicit Potent Mucosal T Cell Immunity to Influenza A Virus

Eliciting durable and protective T cell-mediated immunity in the respiratory mucosa remains a significant challenge. Polylactic-co-glycolic acid (PLGA)-based cationic pathogen-like particles (PLPs) loaded with TLR agonists mimic biophysical properties of microbes and hence, simulate pathogen-pattern...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kingstad-Bakke, Brock, Toy, Randall, Lee, Woojong, Pradhan, Pallab, Vogel, Gabriela, Marinaik, Chandranaik B., Larsen, Autumn, Gates, Daisy, Luu, Tracy, Pandey, Bhawana, Kawaoka, Yoshihoro, Roy, Krishnendu, Suresh, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986715/
https://ncbi.nlm.nih.gov/pubmed/33767689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.559382
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