The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo

KEY POINTS: Reduced vitamin D receptor (VDR) expression prompts skeletal muscle atrophy. Atrophy occurs through catabolic processes, namely the induction of autophagy, while anabolism remains unchanged. In response to VDR‐knockdown mitochondrial function and related gene‐set expression is impaired....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Physiol
Egile Nagusiak: Bass, Joseph J., Kazi, Abid A., Deane, Colleen S., Nakhuda, Asif, Ashcroft, Stephen P., Brook, Matthew S., Wilkinson, Daniel J., Phillips, Bethan E., Philp, Andrew, Tarum, Janelle, Kadi, Fawzi, Andersen, Ditte, Garcia, Amadeo Muñoz, Smith, Ken, Gallagher, Iain J., Szewczyk, Nathaniel J., Cleasby, Mark E., Atherton, Philip J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Muscle
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986223/
https://ncbi.nlm.nih.gov/pubmed/33258480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP280652
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